Cross-sectional study of a United Kingdom cohort of neonatal vein of galen malformation.

ABSTRACT:

Objective

Describe the course and outcomes in a UK national cohort of neonates with vein of Galen malformation identified before 28 days of life.

Methods

Neonates with angiographically confirmed vein of Galen malformation presenting to 1 of 2 UK treatment centers (2006-2016) were included; those surviving were invited to participate in neurocognitive assessment. Results in each domain were dichotomized into "good" and "poor" categories. Cross-sectional and angiographic brain imaging studies were systematically interrogated. Logistic regression was used to explore potential outcome predictors.

Results

Of 85 children with neonatal vein of Galen malformation, 51 had survived. Thirty-four participated in neurocognitive assessment. Outcomes were approximately evenly split

SUBMITTER: Lecce F 

PROVIDER: S-EPMC6221157 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature