Effect of diet protein restriction on progression of chronic kidney disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Dietary protein restriction has long been thought to play an important role in the progression of chronic kidney disease (CKD); however, the effect of dietary protein on the rate of decline in kidney function remains controversial.

Objective

We undertook a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the influence of protein restriction on chronic kidney disease.

Method

Ovid MEDLINE (from 1946 to March 5, 2016), EMBASE (from 1966 to March 5, 2016), and the Cochrane Library (Inception to March 5, 2016) were searched to identify RCTs comparing different levels of protein intake for at least 24 weeks in adult patients with CKD. The outcomes included kidney failure events, the rate of change in estimated glomerular filtra

SUBMITTER: Yan B 

PROVIDER: S-EPMC6221301 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature