The Prevalence of Cerebral Microbleeds in Non-Demented Parkinson's Disease Patients.

ABSTRACT:

Background

Cerebral microbleeds (CMBs) are associated with cerebrovascular risk factors and cognitive dysfunction among patients with Parkinson's disease (PD). However, whether CMBs themselves are associated with PD is to be elucidated.

Methods

We analyzed the presence of CMBs using 3-Tesla brain magnetic resonance imaging in non-demented patients with PD and in age-, sex-, and hypertension-matched control subjects. PD patients were classified according to their motor subtypes: tremor-dominant, intermediate, and postural instability-gait disturbance (PIGD). Other cerebrovascular risk factors and small vessel disease (SVD) burdens were also evaluated.

Results

Two-hundred and five patients with PD and 205 control subjects were included. The prevalence of CMBs was higher

SUBMITTER: Kim KJ 

PROVIDER: S-EPMC6221857 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature