Long- and short-term air pollution exposure and measures of arterial stiffness in the Framingham Heart Study.

ABSTRACT:

Background

Studies of air pollution exposure and arterial stiffness have reported inconsistent results and large studies employing the reference standard of arterial stiffness, carotid-femoral pulse-wave velocity (CFPWV), have not been conducted.

Aim

To study long-term exposure to ambient fine particles (PM_2.5), proximity to roadway, and short-term air pollution exposures in relation to multiple measures of arterial stiffness in the Framingham Heart Study.

Methods

We assessed central arterial stiffness using CFPWV, forward pressure wave amplitude, mean arterial pressure and augmentation index. We investigated long-and short-term air pollution exposure associations with arterial stiffness with linear regressions using long-term residential PM_2.5 (

SUBMITTER: Ljungman PLS 

PROVIDER: S-EPMC6221919 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature