V_E/VCO₂ slope in lean and overweight women and its relationship to lean leg mass.

ABSTRACT: Ventilation/carbon dioxide production (V_E/VCO_2slope) is used clinically to determine cardiorespiratory fitness and morbidity in heart failure (HF). Previously, we demonstrated that lower lean leg mass is associated with high V_E/VCO_2slope during exercise in HF. In healthy individuals, we evaluated 1) whether V_E/VCO_2slope differed between lean and overweight women and 2) the relationship between lean leg mass and V_E/VCO_2slope in overweight sedentary (OWS), overweight trained (OWTR) and lean, trained (LTR) women.

Methods

Gas exchange and ventilation were collected during a treadmill peak oxygen uptake test (VO_2peak) in 40 women [26 OWS (29 ± 7 yrs., mean ± SD), 7 OWTR (33 ± 5 yrs) and 7 L

SUBMITTER: Keller-Ross ML 

PROVIDER: S-EPMC6222036 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature