Characterization of Staphylococcal Cassette Chromosome mec Elements from Methicillin-Resistant Staphylococcus pseudintermedius Infections in Australian Animals.

ABSTRACT: We examined the oxacillin resistance phenotype and genomic structure of staphylococcal cassette chromosome mec (SCCmec) elements from 77 veterinary methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates. Isolates were characterized by oxacillin broth microdilution, whole-genome sequencing, and bioformatics analysis. Five previously described SCCmec elements, and a sixth novel element, were identified: SCCmec III (also known as II-III), ΨSCCmec₅₇₃₉₅, and SCCmec_NA45 (a SCCmec VII variant), all previously described in MRSP, and SCCmec IVg and SCCmec V_T, previously described in both methicillin-resistant Staphylococcus aureus (MRSA) and MRSP. The sixth element was novel

SUBMITTER: Worthing KA 

PROVIDER: S-EPMC6222048 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature