Comparison of Metoprolol and Tramadol with Remifentanil in Endoscopic Sinus Surgery: A Randomised Controlled Trial.

ABSTRACT:

Objective

Controlled hypotension is commonly induced during functional endoscopic sinus surgery to limit mucosal bleeding. This may be detrimental to elderly patients and patients with arterial stenosis. The aim of this pilot study was to determine if a normotensive anaesthetic technique with sufficient analgesia and without profound vasodilation may reduce intraoperative bleeding and incidence of adverse haemodynamic effects associated with vasodilation and variable rate continuous infusions.

Methods

In this double-blind randomised controlled trial in a tertiary care centre, a total of 88 patients were randomised to receive intravenously either 0.1 mg kg^-1 metoprolol and 1 mg kg^-1 tramadol following anaesthesia induction (MT group) or a bolus dose of 0

SUBMITTER: Erdivanlı B 

PROVIDER: S-EPMC6223865 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature