Transcriptome and Proteome of Fish-Pathogenic Streptococcus agalactiae Are Modulated by Temperature.

ABSTRACT: Streptococcus agalactiae is one of the most important pathogens associated with streptococcosis outbreaks in Nile tilapia farms worldwide. High water temperature (above 27°C) has been described as a predisposing factor for the disease in fish. At low temperatures (below 25°C), fish mortalities are not usually observed in farms. Temperature variation can modulate the expression of genes and proteins involved in metabolism, adaptation, and bacterial pathogenicity, thus increasing or decreasing the ability to infect the host. This study aimed to evaluate the transcriptome and proteome of a fish-pathogenic S. agalactiae strain SA53 subjected to in vitro growth at different temperatures using a microarray and label-free shotgun LC-HDMS^E approach. Biological tripl

SUBMITTER: Tavares GC 

PROVIDER: S-EPMC6224512 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature