Metabolic Modeling of Microbial Community Interactions for Health, Environmental and Biotechnological Applications.

ABSTRACT: In nature, microbes do not exist in isolation but co-exist in a variety of ecological and biological environments and on various host organisms. Due to their close proximity, these microbes interact among themselves, and also with the hosts in both positive and negative manners. Moreover, these interactions may modulate dynamically upon external stimulus as well as internal community changes. This demands systematic techniques such as mathematical modeling to understand the intrinsic community behavior. Here, we reviewed various approaches for metabolic modeling of microbial communities. If detailed species-specific information is available, segregated models of individual organisms can be constructed and connected via metabolite exchanges; otherwise, the community may be represented as a

SUBMITTER: Ang KS 

PROVIDER: S-EPMC6225453 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature