Impact of Infectious Diseases Consultation on Mortality of Cryptococcal infection in Patients without HIV.

ABSTRACT:

Background

An infectious disease (ID) consultation is often obtained to treat patients with cryptococcosis due to the complex nature of the disease, but has never been demonstrated to impact outcomes.

Methods

We assembled a retrospective cohort of 147 consecutive cases of cryptococcosis in patients without HIV. Patients who were diagnosed less than 24 hours prior to death were excluded. Survival analysis was performed with Cox regression with survival censored past 90 days.

Results

The patients with an ID consult had a higher fungal burden but a lower 90-day mortality compared to patients without ID involvement (27% vs 45%, p<0.001), with an adjusted hazard ratio of not receiving an ID consult of 4.1 (95% CI: 2.2, 7.6). The ID consult group was more likely to receive

SUBMITTER: Spec A 

PROVIDER: S-EPMC6225890 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature