MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI.

ABSTRACT:

Objectives

The aim of the study was to evaluate CMR myocardial first-pass perfusion in the injured region as well as the non-infarcted area in ST-elevation myocardial infarction (STEMI) patients few days after successful primary percutaneous coronary intervention (PCI).

Materials and methods

220 patients with first time STEMI successfully treated with PCI (with or without postconditioning) were recruited from the Postconditioning in STEMI study. Contrast enhanced CMR was performed at a 1.5 T scanner 2 (1-5) days after PCI. On myocardial first-pass perfusion imaging signal intensity (SI) was measured in the injured area and in the remote myocardium and maximum contrast enhancement index (MCE) was calculated. MCE = (peak SI after contrast-SI at baseline) / SI at baseline x 100

SUBMITTER: Bethke A 

PROVIDER: S-EPMC6226160 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature