Association between death and loss of stage N2 sleep features among critically Ill patients with delirium.

ABSTRACT:

Purpose

Critically ill patients experience significant sleep disruption. In this study of ICU patients with delirium, we evaluated associations between the loss of stage N2 features (K-complexes, sleep spindles), grade of encephalopathy based on electroencephalography (EEG), and intensive care unit (ICU) outcomes. We hypothesized that loss of stage N2 features is associated with more severe grades of encephalopathy and worse ICU outcomes including death.

Materials and methods

This was an observational cohort study of 93 medical ICU patients without primary acute brain injury who underwent continuous EEG. Type and severity of critical illness, sedative-hypnotic use, length of stay, modified Rankin Scale at hospital discharge, and death during hospitalization were abstracted f

SUBMITTER: Knauert MP 

PROVIDER: S-EPMC6226351 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature