Ontology highlight
ABSTRACT:
SUBMITTER: van Wilgenburg B
PROVIDER: S-EPMC6226485 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Nature communications 20181109 1
Mucosal associated invariant T (MAIT) cells are evolutionarily-conserved, innate-like lymphocytes which are abundant in human lungs and can contribute to protection against pulmonary bacterial infection. MAIT cells are also activated during human viral infections, yet it remains unknown whether MAIT cells play a significant protective or even detrimental role during viral infections in vivo. Using murine experimental challenge with two strains of influenza A virus, we show that MAIT cells accumu ...[more]