Risk of colon cancer recurrence in relation to diabetes.

ABSTRACT:

Purpose

To describe the association between diabetes and colon cancer recurrence.

Methods

We conducted a cohort study at two integrated health care delivery systems in the United States. Using tumor registry data, we identified patients aged ≥ 18 years when diagnosed with stage I-IIIA adenocarcinomas of the colon during 1995-2014. Pre-existing diabetes was ascertained via diagnosis codes. Medical records were reviewed for eligibility and to abstract recurrence and covariate information. Recurrence was ascertained beginning 90 days after the end of colon cancer treatment (i.e., cohort entry). Recurrence of any cancer or a new primary cancer at any site was a secondary outcome. We used multivariable Cox proportional hazards models to estimate hazard ratios (HR) and 95% confide

SUBMITTER: Chubak J 

PROVIDER: S-EPMC6230488 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature