Ontology highlight
ABSTRACT:
SUBMITTER: Zhao X
PROVIDER: S-EPMC6230923 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Zhao Xinrui X Zheng Fufu F Li Yizhuo Y Hao Jiaojiao J Tang Zhipeng Z Tian Chunfang C Yang Qian Q Zhu Tianhua T Diao Chaoliang C Zhang Changlin C Chen Manyu M Hu Sheng S Guo Ping P Zhang Lizhi L Liao Yina Y Yu Wendan W Chen Miao M Zou Lijuan L Guo Wei W Deng Wuguo W
Redox biology 20181025
Bromodomain PHD finger transcription factor (BPTF), a core subunit of nucleosome-remodeling factor (NURF) complex, plays an important role in chromatin remodeling. However, its precise function and molecular mechanism involved in hepatocellular carcinoma (HCC) growth are still poorly defined. Here, we demonstrated the tumor-promoting role of BPTF in HCC progression. BPTF was highly expressed in HCC cells and tumor tissues of HCC patients compared with normal liver cells and tissues. Knockdown of ...[more]