Assessing ventilatory instability using the response to spontaneous sighs during sleep in preterm infants.

ABSTRACT: Periodic breathing (PB) is common in newborns and is an obvious manifestation of ventilatory control instability. However, many infants without PB may still have important underlying ventilatory control instabilities that go unnoticed using standard clinical monitoring. Methods to detect infants with "subclinical" ventilatory control instability are therefore required. The current study aimed to assess the degree of ventilatory control instability using simple bedside recordings in preterm infants. Respiratory inductance plethysmography (RIP) recordings were analyzed from ~20 minutes of quiet sleep in 20 preterm infants at 36 weeks post-menstrual age (median [range]: 36 [34-40]). The percentage time spent in PB was also calculated for each infant (%PB). Spontaneous sighs were identified an

SUBMITTER: Edwards BA 

PROVIDER: S-EPMC6231524 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature