Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine.

ABSTRACT: Hemorrhage remains the leading cause of preventable deaths in trauma. Endovascular management of non-compressible torso hemorrhage has been at the forefront of trauma care in recent years. Since complete aortic occlusion presents serious concerns, the concept of partial aortic occlusion has gained a growing attention. Here, we present a large animal model of hemorrhagic shock to investigate the effects of a novel partial aortic balloon occlusion catheter and compare it with a catheter that works on the principles of complete aortic occlusion. Swine are anesthetized and instrumented in order to conduct controlled fixed-volume hemorrhage, and hemodynamic and physiological parameters are monitored. Following hemorrhage, aortic balloon occlusion catheters are inserted and inflated in the supra

SUBMITTER: Williams AM 

PROVIDER: S-EPMC6231876 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature