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The effects of mechanical strain on mouse eye lens capsule and cellular microstructure.


ABSTRACT: The mouse eye lens was used as a model for multiscale transfer of loads. In the lens, compressive strain is distributed across specific lens tissue microstructures, including the extracellular capsule, as well as the epithelial and fiber cells. The removal of high loads resulted in complete recovery of most, but not all, microstructures.

SUBMITTER: Parreno J 

PROVIDER: S-EPMC6232967 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature

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The effects of mechanical strain on mouse eye lens capsule and cellular microstructure.

Parreno Justin J   Cheng Catherine C   Nowak Roberta B RB   Fowler Velia M VM  

Molecular biology of the cell 20180410 16


The mouse eye lens was used as a model for multiscale transfer of loads. In the lens, compressive strain is distributed across specific lens tissue microstructures, including the extracellular capsule, as well as the epithelial and fiber cells. The removal of high loads resulted in complete recovery of most, but not all, microstructures. ...[more]

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