Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial.

ABSTRACT:

Objective

To determine the effects of diets varying in carbohydrate to fat ratio on total energy expenditure.

Design

Randomized trial.

Setting

Multicenter collaboration at US two sites, August 2014 to May 2017.

Participants

164 adults aged 18-65 years with a body mass index of 25 or more.

Interventions

After 12% (within 2%) weight loss on a run-in diet, participants were randomly assigned to one of three test diets according to carbohydrate content (high, 60%, n=54; moderate, 40%, n=53; or low, 20%, n=57) for 20 weeks. Test diets were controlled for protein and were energy adjusted to maintain weight loss within 2 kg. To test for effect modification predicted by the carbohydrate-insulin model, the sample was divided into thirds of pre-weight loss insulin

SUBMITTER: Ebbeling CB 

PROVIDER: S-EPMC6233655 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature