Renal Function, Albuminuria, and the Risk of Cardiovascular Events After Kidney Transplantation.

ABSTRACT:

Background

The risk of mortality and graft loss is higher in kidney transplant recipients with reduced estimated glomerular filtration rate (eGFR) and albuminuria. It is unclear whether these markers are also associated with cardiovascular events.

Methods

We examined linked healthcare databases in Alberta, Canada to identify kidney transplant recipients between 2002 and 2013 who had at least 1 outpatient serum creatinine and albuminuria measurement at 1-year posttransplant. We determined the relationship between categories of eGFR and albuminuria and the risk of subsequent cardiovascular events.

Results

Among 1069 eligible kidney transplant recipients, the median age was 52 years, 37% were female, and 52% had eGFR ≥60 mL/min per 1.73 m². Over a median follo

SUBMITTER: Lam NN 

PROVIDER: S-EPMC6233669 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature