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Accuracy of Digital Pathologic Analysis vs Traditional Microscopy in the Interpretation of Melanocytic Lesions.


ABSTRACT: Importance:Use of digital whole-slide imaging (WSI) for dermatopathology in general has been noted to be similar to traditional microscopy (TM); however, concern has been noted that WSI is inferior for interpretation of melanocytic lesions. Since approximately 1 of every 4 skin biopsies is of a melanocytic lesion, the use of WSI requires verification before use in clinical practice. Objective:To compare pathologists' accuracy and reproducibility in diagnosing melanocytic lesions using Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis (MPATH-Dx) categories when analyzing by TM vs WSI. Design, Setting, and Participants:A total of 87 pathologists in community-based and academic settings from 10 US states were randomized with stratification based on clinical experience to inter

SUBMITTER: Onega T 

PROVIDER: S-EPMC6233746 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature