Association of Apathy With Risk of Incident Dementia: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Fear of dementia is pervasive in older people with cognitive concerns. Much research is devoted to finding prognostic markers for dementia risk. Studies suggest apathy in older people may be prodromal to dementia and could be a relevant, easily measurable predictor of increased dementia risk. However, evidence is fragmented and methods vary greatly between studies.

Objective

To systematically review and quantitatively synthesize the evidence for an association between apathy in dementia-free older individuals and incident dementia.

Data sources

Two reviewers conducted a systematic search of Medline, Embase, and PsychINFO databases.

Study selection

Inclusion criteria were (1) prospective cohort studies, (2) in general populations or memory clinic pati

SUBMITTER: van Dalen JW 

PROVIDER: S-EPMC6233800 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature