Association Between Aortic Vascular Inflammation and Coronary Artery Plaque Characteristics in Psoriasis.

ABSTRACT:

Importance

Inflammation is critical to atherosclerosis. Psoriasis, a chronic inflammatory disease associated with early cardiovascular events and increased aortic vascular inflammation (VI), provides a model to study the process of early atherogenesis. Fludeoxyglucose F 18 positron emission tomography/computed tomography (18F-FDG PET/CT) helps quantify aortic VI, and coronary computed tomography angiography provides coronary artery disease (CAD) assessment through evaluation of total plaque burden (TB) and noncalcified coronary plaque burden (NCB), luminal stenosis, and high-risk plaques (HRP). To our knowledge, association between aortic VI and broad CAD indices has not yet been assessed in a chronic inflammatory disease state. Such a study may provide information regarding the ut

SUBMITTER: Joshi AA 

PROVIDER: S-EPMC6233814 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature