Association of Retinal Neurodegeneration on Optical Coherence Tomography With Dementia: A Population-Based Study.

ABSTRACT:

Importance

Retinal structures may serve as a biomarker for dementia, but longitudinal studies examining this link are lacking.

Objective

To investigate the association of inner retinal layer thickness with prevalent and incident dementia in a general population of Dutch adults.

Design, setting, and participants

From September 2007 to June 2012, participants from the prospective population-based Rotterdam Study who were 45 years and older and had gradable retinal optical coherence tomography images and at baseline were free from stroke, Parkinson disease, multiple sclerosis, glaucoma, macular degeneration, retinopathy, myopia, hyperopia, and optic disc pathology were included. They were followed up until January 1, 2015, for the onset of dementia.

Exposures

Inne

SUBMITTER: Mutlu U 

PROVIDER: S-EPMC6233847 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature