Concurrent chemoradiation therapy tailored to the older adults with esophageal cancer: state of the art and the future.

ABSTRACT:

Purpose

The aim of this study was to review the published literature addressing the question of whether geriatric assessment (GA) should be routinely applied in the treatment of older adults with esophageal cancer (EC) who have received definitive concurrent chemoradiotherapy (dCRT).

Materials and methods

A literature search of PubMed, Embase, and Cochrane Library was performed. Studies that contained original data outlining the inclusion and exclusion criteria, treatment compliance rate, and severe toxicity reports were reviewed. Additionally, criteria from ongoing clinical trials in the World Health Organization and National Institutes of Health registries were reviewed to evaluate the utilization of GA-related domains in elderly EC patients who received dCRT.

Results</

SUBMITTER: Song T 

PROVIDER: S-EPMC6233861 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature