Theoretical and experimental analysis of photon counting detector CT for proton stopping power prediction.

ABSTRACT:

Purpose

Photon counting detectors (PCDs) are being introduced in advanced x-ray computed tomography (CT) scanners. From a single PCD-CT acquisition, multiple images can be reconstructed, each based on only a part of the original x-ray spectrum. In this study, we investigated whether PCD-CT can be used to estimate stopping power ratios (SPRs) for proton therapy treatment planning, both by comparing to other SPR methods proposed for single energy CT (SECT) and dual energy CT (DECT) as well as to experimental measurements.

Methods

A previously developed DECT-based SPR estimation method was adapted to PCD-CT data, by adjusting the estimation equations to allow for more energy spectra. The method was calibrated directly on noisy data to increase the robustness toward image noise.

SUBMITTER: Taasti VT 

PROVIDER: S-EPMC6234096 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature