Early maternal care may counteract familial liability for psychopathology in the reward circuitry.

ABSTRACT: Reward processing is altered in various psychopathologies and has been shown to be susceptible to genetic and environmental influences. Here, we examined whether maternal care may buffer familial risk for psychiatric disorders in terms of reward processing. Functional magnetic resonance imaging during a monetary incentive delay task was acquired in participants of an epidemiological cohort study followed since birth (N = 172, 25 years). Early maternal stimulation was assessed during a standardized nursing/playing setting at the age of 3 months. Parental psychiatric disorders (familial risk) during childhood and the participants' previous psychopathology were assessed by diagnostic interview. With high familial risk, higher maternal stimulation was related to increasing activation in the ca

SUBMITTER: Holz NE 

PROVIDER: S-EPMC6234324 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature