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Effectiveness of contrast-associated acute kidney injury prevention methods; a systematic review and network meta-analysis.


ABSTRACT:

Background

Different methods to prevent contrast-associated acute kidney injury (CA-AKI) have been proposed in recent years. We performed a mixed treatment comparison to evaluate and rank suggested interventions.

Methods

A comprehensive Systematic review and a Bayesian network meta-analysis of randomised controlled trials was completed. Results were tabulated and graphically represented using a network diagram; forest plots and league tables were shown to rank treatments by the surface under the cumulative ranking curve (SUCRA). A stacked bar chart rankogram was generated. We performed main analysis with 200 RCTs and three analyses according to contrast media and high or normal baseline renal profile that includes 173, 112 & 60 RCTs respectively.

Results

We have inclu

SUBMITTER: Ahmed K 

PROVIDER: S-EPMC6234687 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature