Effects of lowering inspiratory oxygen fraction during microvascular decompression on postoperative gas exchange: A pre-post study.

ABSTRACT:

Background

Despite many previous studies, the optimal oxygen fraction during general anesthesia remains controversial. This study aimed to evaluate the effects of lowering intraoperative fraction of inspired oxygen on postoperative gas exchange in patients undergoing microvascular decompression (MVD).

Methods

We conducted a pre-post study to compare postoperative gas exchange with different intraoperative oxygen fractions. From April 2010 to June 2017, 1456 consecutive patients who underwent MVD were enrolled. Starting in January 2014, routine oxygen fraction was lowered from 1.0 to 0.3 during anesthetic induction/awakening and from 0.5 to 0.3 during anesthetic maintenance. Postoperative gas exchange, presented as the minimum value of PaO2/FIO2 ratio within 48 hours, were co

SUBMITTER: Park J 

PROVIDER: S-EPMC6235305 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature