Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: A randomised controlled trial.

ABSTRACT:

Introduction

Neuromuscular weakness resulting in severe functional impairment is common in critical care survivors. This study aimed to evaluate effects of an early progressive rehabilitation intervention in mechanically ventilated adults at risk.

Methods

This was a parallel, two-arm, assessor-blinded, randomised controlled trial with 6-months follow-up that was conducted in a mixed ICU of an academic centre in Switzerland. Previously independent, mechanically ventilated, critically ill adults with expected critical care stay ≥72 hours (n = 115) were randomised to a control group receiving standard physiotherapy including early mobilisation or to an experimental group with early endurance and resistance training combined with mobilisation. Primary endpoints were functional c

SUBMITTER: Eggmann S 

PROVIDER: S-EPMC6235392 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature