Offspring outcomes after prenatal interventions for common mental disorders: a meta-analysis.

ABSTRACT:

Background

It is presumed that pharmacological and non-pharmacological treatment of prenatal common mental disorders can mitigate associated adverse effects in offspring, yet strong evidence for the prophylactic benefits of treatment is lacking. We therefore examined the effect of prenatal treatments for common mental disorders on offspring outcomes.

Methods

For this meta-analysis, articles published up to August 31, 2017, were obtained from PubMed, PsycInfo, Embase, and Cochrane databases. Included studies needed to be randomized controlled trials (RCTs) on the effect of treatment of prenatal common mental disorders comparing an intervention to a control condition, including offspring outcome(s). Random effects models were used to calculate Hedges' g in the program Comprehe

SUBMITTER: Brouwer ME 

PROVIDER: S-EPMC6237028 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature