High-Dose Seasonal Influenza Vaccine in Patients Undergoing Dialysis.

ABSTRACT:

Background and objectives

High-dose influenza vaccine, which contains fourfold more antigen than standard dose, is associated with fewer cases of influenza and less influenza-related morbidity in the elderly general population. Whether the high-dose influenza vaccine benefits patients on dialysis, whose immune response to vaccination is less robust than that of healthy patients, is uncertain.

Design, setting, participants, & measurements

We compared hospitalizations and deaths during the 2015-2016 and 2016-2017 influenza seasons by vaccine type (standard trivalent, standard quadrivalent, and high-dose trivalent influenza vaccine) administered within a national dialysis organization. The association of vaccine type with outcomes was estimated using Cox proportional hazards re

SUBMITTER: Miskulin DC 

PROVIDER: S-EPMC6237058 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature