Ontology highlight
ABSTRACT:
SUBMITTER: Park J
PROVIDER: S-EPMC6237084 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
ACS nano 20171025 11
Kidney transplant patients require life-long surveillance to detect allograft rejection. Repeated biopsy, albeit the clinical gold standard, is an invasive procedure with the risk of complications and comparatively high cost. Conversely, serum creatinine or urinary proteins are noninvasive alternatives but are late markers with low specificity. We report a urine-based platform to detect kidney transplant rejection. Termed iKEA (integrated kidney exosome analysis), the approach detects extracellu ...[more]