Characteristics of AccSTIP1 in Apis cerana cerana and its role during oxidative stress responses.

ABSTRACT: Various environmental stresses, such as heat shock, heavy metals, ultraviolet (UV) radiation and different pesticides, induce a cellular oxidative stress response. The cellular oxidative stress response is usually regulated by heat shock proteins (Hsps) acting as molecular chaperones. Stress-induced phosphoprotein 1 (STIP1), one of the most widely studied co-chaperones, functions as an adaptor that directs Hsp90 to Hsp70-client protein complexes. However, the biological functions of STIP1 remain poorly understood in honeybee (Apis cerana cerana). In this study, AccSTIP1 was identified in Apis cerana cerana. AccSTIP1 transcription was found to be induced by heat (42 °C), HgCl₂, H₂O₂ and different pesticides (emamectin benzoate, thiamethoxam, hexythiazox and

SUBMITTER: Zhai N 

PROVIDER: S-EPMC6237692 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature