Height, waist circumference, body mass index, and body somatotype across the life course and risk of glioma.

ABSTRACT:

Purpose

Recent studies have suggested height as a risk factor for glioma, but less is known regarding body mass index (BMI) or other anthropomorphic measures. We evaluated the association between body habitus and risk of glioma.

Methods

We evaluated the association of measures of height, BMI, waist circumference, and somatotypes with risk of glioma in two prospective cohorts, the Nurses' Health Study and the Health Professionals Follow-Up Study.

Results

We documented 508 incident cases of glioma (321 glioblastoma [GBM]). In both cohorts, we found no significant association between adult BMI or waist circumference and risk of glioma, with pooled HR for BMI of 1.08 (95% CI 0.85-1.38 comparing ≥ 30 to < 25 kg/m²) and for waist circumference of 1.05 (95% CI 0.8

SUBMITTER: Cote DJ 

PROVIDER: S-EPMC6238636 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature