Inflammatory and coagulatory parameters linked to survival in critically ill children with sepsis.

ABSTRACT:

Background

Sepsis is associated with a deflection of inflammatory and coagulative parameters, since some clotting factors are known to be involved in the host's defense against infection and inflammation. These parameters could play a crucial role in the course of sepsis and be used as prognostic markers in critically ill children.

Methods

A total of 250 critically ill pediatric patients diagnosed with sepsis were retrospectively analyzed to identify routinely measured predictors for in-hospital mortality at the peak level of C-reactive protein. Those parameters entered multivariate logistic regression analysis as well as a decision tree for survival.

Results

Multivariate logistic regression analysis revealed fibrinogen, platelets and activated partial thromboplastin

SUBMITTER: Niederwanger C 

PROVIDER: S-EPMC6240023 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature