Therapeutic effects of bee venom and its major component, melittin, on atopic dermatitis in vivo and in vitro.

ABSTRACT:

Background and purpose

Atopic dermatitis (AD) is a multifactorial skin condition with complex interactions of innate and adaptive immune responses. There are several existing therapies for AD, including topical glucocorticosteroids, emollients, phototherapies, calcineurin inhibitors and immunosuppressants, such as cyclosporine A. Although these therapies reduce inflammation, they also cause serious side effects. Therefore, it is necessary to develop new therapeutic approaches for AD treatment without side effects. There are several studies on natural materials or toxins, such as herbs, ginseng extract and snake venom, for AD treatment. However, treatment of AD with bee venom and its major component, melittin has rarely been studied.

Experimental approach

Effects of bee venom

SUBMITTER: An HJ 

PROVIDER: S-EPMC6240132 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature