Case report: two confirmed cases of human Seoul virus infections in Indonesia.

ABSTRACT:

Background

Seoul virus (SEOV) is a member of hantavirus family, which is transmitted to humans by Rattus rattus and Rattus norvegicus. Diagnosing SEOV infection is difficult because the clinical presentations are often undifferentiated with other viral or bacterial infections and assays to test antibodies seroconversion and RNA detection are not available in resource-limited setting like Indonesia.

Case presentation

We report two confirmed cases of SEOV infection from Indonesia. Here, we illustrate the clinical presentations, hematology and biochemistry profiles, and outcomes of the two cases. Phylogenetic analysis revealed that SEOV sequences have highest homology to isolates obtained from rodents in Indonesia.

Conclusions

This report highlights the importance of con

SUBMITTER: Lie KC 

PROVIDER: S-EPMC6240170 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature