Paternal factors contributing to embryo quality.

ABSTRACT:

Purpose

Advancing maternal and paternal age leads to a decrease in fertility, and hence, many infertile couples opt for assisted reproductive technologies [ART] to achieve biological parenthood. One of the key determinants of achieving a live outcome of ART, embryo quality, depends on both the quality of the oocyte and sperm that have created the embryo. Several studies have explored the effect of oocyte parameters on embryo quality, but the effects of sperm quality on the embryo have not been comprehensively evaluated.

Method

In this review, we assess the effect of various genetic factors of paternal origin on the quality and development of the embryo.

Results

The effects of sperm aneuploidy, sperm chromatin structure, deoxyribonucleic acid [DNA] fragmentation, role

SUBMITTER: Colaco S 

PROVIDER: S-EPMC6240539 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature