Standardization of ⁶⁴Cu activity.

ABSTRACT: The complex decay scheme that makes ⁶⁴Cu promising as both an imaging and therapeutic agent in medicine also makes the absolute measurement of its activity challenging. The National Institute of Standards and Technology (NIST) has completed a primary activity standardization of a ⁶⁴CuCl₂ solution using the 4πβ(LS)-γ(NaI) live-timed anticoincidence (LTAC) counting method with a combined standard uncertainty of 0.51 %. Two liquid scintillation (LS) counting methods were employed for confirmatory measurements. Secondary measurements were made by high-purity germanium detectors, pressurized ionization chambers (IC), and a well-type NaI(Tl) counter. Agreement between the LTAC-based standard and standards from other laboratories was established via IC calibration

SUBMITTER: Bergeron DE 

PROVIDER: S-EPMC6240916 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature