Inflammation and psychopathology in children following PICU admission: an exploratory study.

ABSTRACT:

Background

Survivors of critical illness in childhood commonly display subsequent psychiatric symptoms including emotional and behavioural difficulties, and manifestations of post-traumatic stress disorder (PTSD). Anomalies in inflammatory profiles are an established finding in these childhood psychiatric conditions.

Objective

This exploratory study aimed to investigate whether abnormal peripheral blood inflammatory markers measured during paediatric intensive care unit (PICU) admission were associated with psychiatric symptoms after discharge.

Methods

We performed a prospective observational cohort study on 71 children with septic illness, meningoencephalitis and other critical disorders admitted to two PICUs between 2007 and 2010. 3-6 months following discharge, sub

SUBMITTER: Caspani G 

PROVIDER: S-EPMC6241628 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature