Extubation from high-frequency oscillatory ventilation in extremely low birth weight infants: a prospective observational study.

ABSTRACT:

Objective

To evaluate if weaning from high-frequency oscillatory ventilation (HFOV) directly to a non-invasive mode of respiratory support is feasible and results in successful extubation in extremely low birth weight (ELBW) infants.

Design

Prospective observational study.

Setting

Tertiary neonatal intensive care unit.

Patients

One hundred and eight ELBW infants of 26.2±1.4 weeks of gestational age (GA) directly extubated from HFOV.

Interventions

All infants were managed with elective HFOV and received surfactant after a recruitment HFOV manoeuvre. Extubation was attempted at mean airways pressure (MAP) ≤6 cm H₂O with FiO₂ ≤0.25. After extubation, all infants were supported by nasal continuous positive airway pressure (6-8 cm H

SUBMITTER: Tana M 

PROVIDER: S-EPMC6242018 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature