Performance and variability of QuantiFERON Gold Plus assay associated with phlebotomy type.

ABSTRACT:

Background

QuantiFERON Gold Plus (Plus) assay has two approved methods for blood collection: direct in-tube (Plus direct) or the transfer of blood from a lithium heparin tube (Plus transfer). Currently, there is little data comparing the results of Plus and the QuantiFERON Gold In-Tube (Gold) based on blood collection.

Methods

In 2017, high risk healthcare workers undergoing annual tuberculosis infection screening at Houston Methodist Hospital, a private hospital in the Texas Medical Center (Houston, TX, U.S.A.) were consented and enrolled in a study comparing the Gold-in-tube (Gold), Plus direct in-tube, and Plus transfer assays. Blood was drawn concurrently for all 3 assays.

Results

Phlebotomy occurred on 300 consecutive, consented and enrolled participants in the s

SUBMITTER: Agarwal S 

PROVIDER: S-EPMC6242684 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature