Diagnostic accuracy of salivary gland ultrasonography with different scoring systems in Sjogren's syndrome: a systematic review and meta-analysis.

ABSTRACT: Noninvasive objective salivary gland ultrasonography (SGU) had been widely used to evaluate major salivary gland involvement in primary Sjögren's syndrome (pSS) and treatment responses. However, the evaluation score, diagnostic sensitivity, and diagnostic specificity significantly varied among clinical studies. We conducted this meta-analysis to assess the diagnostic accuracy of different SGU scoring systems using the American-European Consensus Group criteria. Of the 1301 articles retrieved from six databases, 24 met the criteria for quality assessment and 14 for meta-analyses. The pooled sensitivities were 75% (0-4) with I² = 92.0%, 84% (0-16) with I² = 63.6%, and 75% (0-48) with I² = 90.9%; the pooled specificities were 93% (0-4) with I² = 71.

SUBMITTER: Zhou M 

PROVIDER: S-EPMC6244082 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature