Comparing the impact of older age on outcome in chronic kidney disease of different etiologies: a prospective cohort study.

ABSTRACT:

Background

In older patients with chronic kidney disease (CKD), the risk of progression to end stage renal disease and cardiovascular death both differ compared to younger patients. This likely reflects differences in case mix and co-morbid burdens. We sought to establish the extent to which age itself is an independent biomarker of adverse outcome in CKD.

Methods

This was an analysis of the Salford Kidney Study, a prospective, longitudinal, observational study of 2,667 patients with eGFR < 60 ml/min/1.73 m². Patients were divided into four age groups (< 55, 55-65, 65-75 and > 75 years). Within group adjusted hazard ratios for death in older compared to younger patients were calculated for different primary renal diseases. A competing risk model of death and renal

SUBMITTER: Raman M 

PROVIDER: S-EPMC6244557 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature