Effectiveness of medical treatment for Cushing's syndrome: a systematic review and meta-analysis.

ABSTRACT:

Purpose

To systematically review the effectiveness of medical treatment for Cushing's syndrome in clinical practice, regarding cortisol secretion, clinical symptom improvement, and quality of life. To assess the occurrence of side effects of these medical therapies.

Methods

Eight electronic databases were searched in March 2017 to identify potentially relevant articles. Randomized controlled trials and cohort studies assessing the effectiveness of medical treatment in patients with Cushing's syndrome, were eligible. Pooled proportions were reported including 95% confidence intervals.

Results

We included 35 articles with in total 1520 patients in this meta-analysis. Most included patients had Cushing's disease. Pooled reported percentage of patients with normalization

SUBMITTER: Broersen LHA 

PROVIDER: S-EPMC6244780 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature