First Look at Control-IQ: A New-Generation Automated Insulin Delivery System.

ABSTRACT:

Objective

To pilot test a new closed-loop control technology to validate it for a further large clinical trial.

Research design and methods

The t:slim X2 insulin pump with Control-IQ Technology (Tandem Diabetes Care) includes a Dexcom G6 sensor and a closed-loop algorithm implemented in the pump that 1) automates insulin correction boluses, 2) has a dedicated hypoglycemia safety system, and 3) gradually intensifies control overnight, aiming for blood glucose levels of approximately 100-120 mg/dL every morning.

Results

Five patients with type 1 diabetes (mean age 52.8 years, 2/3 male/female, mean A1C 6.5%) used Control-IQ in an outpatient setting (hotel) for approximately 37 h. During the closed loop, mean glucose was 129 mg/dL (135/121 mg/dL durin

SUBMITTER: Brown S 

PROVIDER: S-EPMC6245207 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature