The overlap syndrome of urticaria and gastroesophageal reflux disease.

ABSTRACT:

Background

One-quarter of systemic symptoms associated with chronic spontaneous urticaria (CSU) are related to gastrointestinal complaints (GICs).

Objectives

To investigate the prevalence and features of urticaria-overlapping GICs.

Methods

In this retrospective cross-sectional survey, 1426 consecutive outpatients were observed at our University Department. Only patients suffering from urticaria or GICs with a complete diagnostic work-up including serum total IgE level (Tot-IgE), differential blood count and urticaria activity score (UAS), were evaluated.

Results

Among different GICs, gastroesophageal reflux disease (GERD) was the most frequent syndrome observed (15.4%; 95%CI: 13.6-17.3). The prevalence of overlap syndrome for urticaria and GERD was 5.9% (95%CI:

SUBMITTER: Aitella E 

PROVIDER: S-EPMC6245739 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature