Shifting ground and gaps in transfusion support of patients with hematological malignancies.

ABSTRACT: The transfusion support of hematological malignancies considers 2 dimensions: the quantity of what we order (in terms of triggers, doses, targets, and intervals), and the special qualities thereof (with respect to depths of matching and appropriate product modifications). Meanwhile, transfusion-related enhancements in the quantity and quality of life may not be dose dependent but rather tempered by unintended patient harms and system strains from overexposure. Evidence and guidelines concur in endorsing clinically noninferior conservative red blood cell (RBC) transfusion care strategies (eg, triggering at hemoglobin <7-8 g/dL and in single-unit doses for stable, nonbleeding inpatients). However, the unique subpopulation of patients with hematological malignancies who are increasingly manag

SUBMITTER: Cserti-Gazdewich C 

PROVIDER: S-EPMC6246005 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature