Silver and Copper Acute Effects on Membrane Proteins and Impact on Photosynthetic and Respiratory Complexes in Bacteria.

ABSTRACT: Silver (Ag⁺) and copper (Cu⁺) ions have been used for centuries in industry, as well as antimicrobial agents in agriculture and health care. Nowadays, Ag⁺ is also widely used in the field of nanotechnology. Yet, the underlying mechanisms driving toxicity of Ag⁺ ions in vivo are poorly characterized. It is well known that exposure to excess metal impairs the photosynthetic apparatus of plants and algae. Here, we show that the light-harvesting complex II (LH2) is the primary target of Ag⁺ and Cu⁺ exposure in the purple bacterium Rubrivivax gelatinosus Ag⁺ and Cu⁺ specifically inactivate the 800-nm absorbing bacteriochlorophyll a (B800), while Ni²⁺ or Cd²⁺ treatme

SUBMITTER: Tambosi R 

PROVIDER: S-EPMC6247083 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature